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Addiction pfacvhe lc. The interaction of neurotransmitters and genes that control the release of dopamine is the Brain Reward Cascade (BRC) Variations within the BRC, whether genetic or epigenetic, may predispose individuals to addictive behaviors and altered pain tolerance This discussion authored by a. P l e a s e i n d i c a t e t h e a m o u n t o f a s s i s t a n c e y o u a r e r e q u e s t i n g * Select Option Note Submission of this form does not guarantee grant funds. Jan 22, 21 · Addiction is a major issue in the United States An estimated 4 million Americans age 12 or older (74%) experienced addiction in the last year 1 However, in 19, only 42 million people (15%) received some type of care and only 26 million people (1%) received specialized addiction treatment 1 Treatment can be expensive, and many people struggle to pay for care.
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